Palliative Care
Candida Infections
This type of fungal infection can arise from dry mouth, dentures and immunosuppression.
Species that are responsible for causing such infection include Candida albicans, C glabrata, C dubliniensis and C tropicalis.
There are different forms in which the candida infection can present;
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Pseudomembraneous
White patches on the tongue which can be removed painlessly by abrasion to reveal mucosal surface.
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Erythrematous
Reddened and sore mucosal surface in the oral cavity but more commonly seen on the tongue.
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Angular cheilitis
Reddened soreness in the corner of the mouth.
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Denture stomatitis
Soreness in the area surrounding the denture in the mouth
The candida infection may spread to other areas in proximal location such as the oesophagus.
Treatment:
In immunocompetant: A course of topical nystatin (1ml to rinse and swallowed 4 times a
day for a period of 7-14 days) or miconazole is recommended. If nystatin is given, dentures
should be removed prior to admministration of the drug and must wait for 30 minutes following chlorhexidine use or else nystatin will be deactivated.
In cases of persistent candiasis that do not respond to topical treatment, oral fluconazole can be considered.
Immunocompromised: A course of high dose fluconazole (50mg) for 7-14 days should be
considered.


