Causes of pain

 

This could be disease related such as cancer metastases and compression of the surrounding

structures. This includes:

 

 Bone pain due to cancer metastases or inability to tolerate

pressure

 

 Liver pain arising from hepatomegaly (enlargement of the

liver) and tenderness of upper right quadrant.

 

 Nerve pain (compression of nerves by tumour)

 

 Raised intracranial pressure

 

 Cramping pain in the abdomen (due to bowel obstruction or

 bladder spasm)

 

 Treatment induced  (chemotherapy neuropathy, 

opioid induced constipation and damaged mucosal membrane due to radiation)

 

 Debility related such as pressure sores arising from prolonged period of

confinement in bed, oral candiasis and severe cachexia.

 

 Other conditions such as arthritis and osteoporosis.